Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6855100 | 1.00 | LMNA (0.62) | LMNAALDH1A1GAAMAPTKMT2A | |
| SCHEMBL21121252 | 0.99 | LMNA (0.64) | LMNAALDH1A1GAAMAPTKMT2A | |
| SCHEMBL5245970 | 0.85 | L3MBTL1 (0.47) | LMNAALDH1A1GAAMAPTKMT2A | |
| SCHEMBL18919378 | 0.85 | L3MBTL1 (0.47) | LMNAALDH1A1GAAMAPTKMT2A | |
| SCHEMBL17941037 | 0.83 | L3MBTL1 (0.48) | LMNAALDH1A1GAAMAPTKMT2A | |
| SCHEMBL26813921 | 0.83 | TGM2 (0.53) | LMNAMAPTCA1CA2RAB9A | |
| SCHEMBL23303502 | 0.82 | LMNA (0.50) | LMNAALDH1A1KMT2ACA1CA2 | |
| SCHEMBL26979071 | 0.82 | ALDH1A1 (0.48) | LMNAALDH1A1GAAMAPTCA1 | |
| SCHEMBL25206305 | 0.82 | ALDH1A1 (0.48) | LMNAALDH1A1GAAMAPTCA1 | |
| SCHEMBL9872166 | 0.82 | ALDH1A1 (0.48) | LMNAALDH1A1GAAMAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024102970-A1 | COMPOUNDS FOR MODULATING SYK ACTIVITY AND E3 UBIQUITIN LIGASE ACTIVITY | Kronos Bio, Inc. (US) | 2024-05-16 | — | — | WO | disclosed |