Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854868 | 0.78 | MAOB (0.46) | HTR1AHTR1DHTR1BKDM4EALDH1A1 | |
| SCHEMBL6141047 | 0.75 | KDM4E (0.45) | KDM4EALDH1A1HRH3CHRNB2CHRNA4 | |
| SCHEMBL6436102 | 0.74 | KDM4E (0.54) | HTR1AKDM4EALDH1A1KMT2A | |
| SCHEMBL14922281 | 0.73 | HRH3 (0.57) | KDM4EALDH1A1HRH3KMT2AHPGD | |
| SCHEMBL6588597 | 0.72 | HRH3 (0.66) | KDM4EALDH1A1HRH3KMT2A | |
| SCHEMBL6141505 | 0.71 | DHFR (0.36) | HTR1AHTR1DHTR1BALDH1A1HRH3 | |
| SCHEMBL30852680 | 0.71 | ROCK1 (0.44) | KDM4EALDH1A1HRH3MGLLABHD6 | |
| SCHEMBL17324776 | 0.70 | HRH3 (0.47) | HRH3CHRNB2CHRNA4 | |
| SCHEMBL14625869 | 0.68 | HRH3 (0.43) | KDM4EALDH1A1HRH3MGLLABHD6 | |
| SCHEMBL6141571 | 0.67 | CHRNB2 (0.58) | KDM4EALDH1A1HRH3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515940-A2 | AMINOALKOXY-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2005-03-23 | — | — | EP | disclosed |
| WO-2003097574-A2 | AMINOALKOXY-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2003-11-27 | — | — | WO | disclosed |