Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 12/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30853318 | 0.75 | BTK (0.39) | BTK | |
| SCHEMBL16382698 | 0.67 | BTK (0.50) | BTKALDH1A1 | |
| SCHEMBL17699610 | 0.63 | BTK (0.50) | BTK | |
| SCHEMBL19009090 | 0.58 | BTK (0.43) | BTKALDH1A1 | |
| SCHEMBL26240985 | 0.58 | MAP2K2 (0.42) | SLC9A1ALDH1A1TSHR | |
| SCHEMBL2588267 | 0.56 | ALDH1A1 (0.50) | BTKALDH1A1NPSR1 | |
| SCHEMBL29926543 | 0.56 | ALDH1A1 (0.50) | BTKALDH1A1NPSR1 | |
| SCHEMBL16382703 | 0.56 | BTK (0.45) | BTK | |
| SCHEMBL20674101 | 0.56 | IKBKB (0.39) | BTKIKBKBALDH1A1 | |
| SCHEMBL9936768 | 0.56 | BTK (0.42) | BTKIKBKBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |