Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | CDC25B | P30305 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | APAF1 | O14727 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1872809 | 1.00 | KDM4E (0.53) | KDM4EGAAALDH1A1NPSR1HTT | |
| SCHEMBL15367087 | 0.83 | KDM4E (0.63) | KDM4EGAAALDH1A1HTTHPGD | |
| SCHEMBL14743916 | 0.80 | CHEK1 (0.48) | KDM4EGAAPARP1GLACYP1A2 | |
| SCHEMBL19953791 | 0.80 | CHEK1 (0.48) | KDM4EGAAALDH1A1NPSR1HTT | |
| SCHEMBL29430150 | 0.80 | HPGD (0.62) | KDM4EGAAALDH1A1HPGDPARP1 | |
| SCHEMBL2815600 | 0.80 | HPGD (0.62) | KDM4EGAAALDH1A1HPGDPARP1 | |
| SCHEMBL8985899 | 0.79 | ALDH1A1 (0.67) | KDM4EGAAALDH1A1NPSR1HPGD | |
| SCHEMBL175459 | 0.78 | LOXL2 (0.54) | KDM4EGAAALDH1A1HPGDPARP1 | |
| SCHEMBL519591 | 0.78 | KDM4E (0.69) | KDM4EGAAALDH1A1HPGDXDH | |
| SCHEMBL29751000 | 0.78 | LOXL2 (0.54) | KDM4EGAAALDH1A1HPGDPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397822-B | CBP/EP300 inhibitors and uses thereof | 南京药石科技股份有限公司 | 2024-04-16 | — | — | CN | disclosed |