Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | CDC25B | P30305 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | APAF1 | O14727 | 6/20 | 0.46 |
| ▸ | CASP3 | P42574 | 5/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 5/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 4/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | UBE2I | P63279 | 2/20 | 0.46 |
| ▸ | GALK1 | P51570 | 1/20 | 0.46 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175459 | 1.00 | LOXL2 (0.54) | LOXL2KDM4EGAACDC25BALDH1A1 | |
| SCHEMBL2815600 | 0.84 | HPGD (0.62) | LOXL2KDM4EGAACDC25BALDH1A1 | |
| SCHEMBL29430150 | 0.84 | HPGD (0.62) | LOXL2KDM4EGAACDC25BALDH1A1 | |
| SCHEMBL30853483 | 0.78 | KDM4E (0.53) | LOXL2KDM4EGAACDC25BALDH1A1 | |
| SCHEMBL16008410 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1872809 | 0.78 | KDM4E (0.53) | LOXL2KDM4EGAACDC25BALDH1A1 | |
| SCHEMBL4002866 | 0.77 | MAP2K1 (0.35) | LOXL2KDM4EGAAPARP1 | |
| SCHEMBL118686 | 0.76 | FLT3 (0.71) | KDM4EGAAALDH1A1HPGDMAPT | |
| SCHEMBL29362757 | 0.76 | FLT3 (0.71) | KDM4EGAAALDH1A1HPGDMAPT | |
| SCHEMBL717595 | 0.74 | KIF11 (0.44) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3472149-B1 | HETEROCYCLIC PROLINAMIDE DERIVATIVES | Orion Ophthalmology LLC (US) | 2023-08-30 | — | — | EP | claimed |
| CN-114685453-A | Heterocyclic prolinamide derivatives | 奥瑞恩眼科有限责任公司 | 2022-07-01 | — | — | CN | disclosed |