Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | PLK4 | O00444 | 2/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.43 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.43 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30438815 | 0.90 | PRMT6 (0.53) | AGXTACHENTRK1MAPTKDM4E | |
| SCHEMBL30855015 | 0.87 | AGXT (0.48) | AGXTACHENTRK1ADORA3PLOD2 | |
| SCHEMBL30854968 | 0.86 | KDM4E (0.57) | ACHEPLK4MAPTHTTKDM4E | |
| SCHEMBL30854948 | 0.79 | KDM4E (0.69) | AGXTPLK4NTRK1MAPTHTT | |
| SCHEMBL30855009 | 0.79 | HDAC3 (0.53) | PLK4NTRK1HDAC1CAMK2D | |
| SCHEMBL30854953 | 0.77 | AGXT (0.48) | AGXTACHEPLK4NTRK1MAPT | |
| SCHEMBL30854998 | 0.77 | GAA (0.51) | ACHEPLK4MAPTHTTKDM4E | |
| SCHEMBL30854949 | 0.77 | L3MBTL1 (0.60) | AGXTPLK4NTRK1MAPTHTT | |
| SCHEMBL1038303 | 0.74 | PRMT6 (0.72) | AGXTNTRK1MAPTKDM4EHDAC4 | |
| SCHEMBL30854951 | 0.73 | NCF1 (0.50) | ACHEMAPTHTTKDM4EALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | claimed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |