Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.31 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29334427 | 1.00 | KMO (0.33) | KMOMAP3K12ASIC3 | |
| SCHEMBL29334426 | 0.71 | KRAS (0.34) | — | |
| SCHEMBL29334239 | 0.64 | KMO (0.38) | KMO | |
| SCHEMBL30855130 | 0.64 | KMO (0.38) | KMO | |
| SCHEMBL29333545 | 0.63 | MAPK1 (0.33) | — | |
| SCHEMBL29334357 | 0.60 | PRKACA (0.39) | — | |
| SCHEMBL31008561 | 0.58 | ASIC3 (0.50) | KMOASIC3 | |
| SCHEMBL29334233 | 0.56 | METTL3 (0.32) | — | |
| SCHEMBL31224163 | 0.55 | — | — | |
| SCHEMBL25344301 | 0.53 | IDH1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4594308-A1 | N-ACRYLOYLMORPHOLINE DERIVATIVES AS KEAP1 MODULATORS AND USES THEREOF | Vividion Therapeutics, Inc. (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024073587-A1 | N-ACRYLOYLMORPHOLINE DERIVATIVES AS KEAP1 MODULATORS AND USES THEREOF | VIVIDION THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |