SCHEMBL30859565

SCHEMBL30859565

COC(=O)c1cc(=O)n(C2CCN(C(=O)OC(C)(C)C)CC2)cc1OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 2/20 0.45
EED O75530 1/20 0.45
RBBP4 Q09028 1/20 0.45
SUZ12 Q15022 1/20 0.45
EZH2 Q15910 1/20 0.45
AEBP2 Q6ZN18 1/20 0.45
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 3/20 0.43
MAPT P10636 2/20 0.43
THRB P10828 1/20 0.43
PDE4B Q07343 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
PDE4A P27815 2/20 0.42
PDE4C Q08493 2/20 0.42
PDE4D Q08499 2/20 0.42
CTSD P07339 1/20 0.42
CTSE P14091 1/20 0.42
BACE1 P56817 1/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30859613 0.90 ALDH1A1 (0.48) STSALDH1A1KDM4EMAPTTHRB
SCHEMBL27190643 0.88 EED (0.46) STSEEDRBBP4SUZ12EZH2
SCHEMBL30859547 0.81 CRBN (0.53) ALDH1A1KDM4EMAPTTHRBMEN1
SCHEMBL27191110 0.80 KDM4E (0.45) ALDH1A1KDM4EMAPTTHRBMEN1
SCHEMBL27190592 0.79 REV1 (0.40) EEDRBBP4SUZ12EZH2AEBP2
SCHEMBL16669749 0.78 ALDH1A1 (0.46) STSEEDRBBP4SUZ12EZH2
SCHEMBL27190975 0.77 ALDH1A1 (0.38) EEDRBBP4SUZ12EZH2AEBP2
SCHEMBL3244599 0.76 HCAR1 (0.48) STSEEDRBBP4SUZ12EZH2
SCHEMBL26243043 0.76 ALDH1A1 (0.45) EEDRBBP4SUZ12EZH2AEBP2
SCHEMBL34469627 0.75 EED (0.46) STSEEDRBBP4SUZ12EZH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024073475-A9 CEREBLON LIGANDS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A/ SK LIFE SCIENCE LABS (US) 2025-04-24 WO disclosed
WO-2024073475-A1 CEREBLON LIGANDS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) 2024-04-04 WO disclosed