Glutarate

Glutarate

SCHEMBL30862146

N=C(N)NN.O=C(O)CCCC(=O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.55
KDM4E B2RXH2 1/20 0.48
KDM5C P41229 1/20 0.48
PHF8 Q9UPP1 1/20 0.48
KDM2A Q9Y2K7 1/20 0.48
LMNA P02545 5/20 0.48
TSHR P16473 4/20 0.46
CYP1A2 P05177 2/20 0.46
THRB P10828 2/20 0.46
BLM P54132 2/20 0.46
KMT2A Q03164 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
GABRR3 A8MPY1 1/20 0.46
GABRP O00591 1/20 0.46
GABRD O14764 1/20 0.46
HDAC3 O15379 1/20 0.46
GABBR2 O75899 1/20 0.46
GABRA1 P14867 1/20 0.46
GABRB1 P18505 1/20 0.46
GABRG2 P18507 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adipic Acid SCHEMBL30862135 0.95 LMNA (0.55) SLC22A6KDM4EKDM5CPHF8KDM2A
Succinic Acid SCHEMBL30862138 0.90 KDM4E (0.59) SLC22A6KDM4EKDM5CPHF8KDM2A
Succinic Acid SCHEMBL28239345 0.90 KDM4E (0.59) SLC22A6KDM4EKDM5CPHF8KDM2A
Glutarate SCHEMBL4148651 0.84 SLC22A6 (0.69) SLC22A6LMNATSHRCYP1A2THRB
Pimagedine SCHEMBL27540257 0.83 KDM4E (0.46) SLC22A6KDM4EKDM5CPHF8KDM2A
Malonic Acid SCHEMBL508810 0.81 LDHA (0.53) KDM4EKDM5CPHF8KDM2ALMNA
Butyric Acid SCHEMBL11745812 0.81 FFAR3 (0.59) SLC22A6KDM4EKDM5CPHF8KDM2A
Alpha-Ketoglutaric Acid SCHEMBL30862136 0.79 EGLN1 (0.61) SLC22A6KDM4EKDM5CPHF8KDM2A
Levulinic Acid SCHEMBL27582435 0.79 LMNA (0.61) KDM4EKDM5CPHF8KDM2ALMNA
SCHEMBL2510241 0.79 SLC22A6 (0.48) SLC22A6KDM4EKDM5CPHF8KDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117836271-A Salts of phenylpyrrolaminoguanidine and polymorphs of phenylpyrrolaminoguanidine onium salts 西奈克制药有限公司 2024-04-05 CN claimed
CN-117836271-A Salts of phenylpyrrolaminoguanidine and polymorphs of phenylpyrrolaminoguanidine onium salts 西奈克制药有限公司 2024-04-05 CN disclosed