Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.52 |
| ▸ | GBA1 | P04062 | 5/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | ITPR3 | Q14573 | 5/20 | 0.43 |
| ▸ | ITPR2 | Q14571 | 1/20 | 0.42 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.42 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3080816 | 1.00 | LPAR3 (0.52) | LPAR3LPAR1LPAR2GBA1PDPK1 | |
| SCHEMBL7751818 | 1.00 | LPAR3 (0.52) | LPAR3LPAR1LPAR2GBA1PDPK1 | |
| SCHEMBL3081758 | 0.98 | LPAR3 (0.55) | LPAR3LPAR1LPAR2GBA1PDPK1 | |
| SCHEMBL3086058 | 0.98 | LPAR3 (0.55) | LPAR3LPAR1LPAR2GBA1PDPK1 | |
| SCHEMBL8496685 | 0.94 | PDPK1 (0.47) | LPAR3LPAR1LPAR2GBA1PDPK1 | |
| SCHEMBL3069188 | 0.94 | PDPK1 (0.47) | LPAR3LPAR1LPAR2GBA1PDPK1 | |
| SCHEMBL8500649 | 0.94 | PDPK1 (0.47) | LPAR3LPAR1LPAR2GBA1PDPK1 | |
| SCHEMBL3073627 | 0.94 | PDPK1 (0.47) | LPAR3LPAR1LPAR2GBA1PDPK1 | |
| SCHEMBL3075480 | 0.88 | GBA1 (0.66) | LPAR3LPAR1LPAR2GBA1ITPR3 | |
| SCHEMBL14094694 | 0.87 | PDPK1 (0.42) | LPAR3LPAR1LPAR2GBA1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100261682-A1 | Method and Means for the Treatment of Cachexia | BIONERIS AB | 2010-10-14 | — | — | US | claimed |
| US-20160074421-A1 | METHOD FOR THE TREATMENT OF DISEASES CAUSED BY HAEMORRHAGIC VIRUSES AND COMPOUNDS FOR USE IN SAID TREATMENT | SIRÈN MATTI (FI) | 2016-03-17 | — | — | US | disclosed |
| US-20100261682-A1 | Method and Means for the Treatment of Cachexia | BIONERIS AB | 2010-10-14 | — | — | US | disclosed |
| EP-2187892-A1 | METHOD AND MEANS FOR THE TREATMENT OF CACHEXIA | Bioneris AB (SE) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009038533-A1 | METHOD AND MEANS FOR THE TREATMENT OF CACHEXIA | BIONERIS AB (SE) | 2009-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261682-A1 | Method and Means for the Treatment of Cachexia | PYGM, GYS1, CPT1B | LPAR3 1154/4885LPAR1 2004/4885LPAR2 1904/4885 |
| US-20160074421-A1 | METHOD FOR THE TREATMENT OF DISEASES CAUSED BY HAEMORRHAGIC VIRUSES AND COMPOUNDS FOR USE IN SAID TREATMENT | TTPA, LPO, HADHB | LPAR3 3383/4885LPAR1 3051/4885LPAR2 3067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.