Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27118478 | 0.88 | FFAR4 (0.35) | KDM1AMAOBADRA2C | |
| SCHEMBL22835375 | 0.82 | — | — | |
| SCHEMBL26105435 | 0.81 | KDM1A (0.33) | KDM1AMAOB | |
| SCHEMBL28893 | 0.79 | ITGB3 (0.42) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL146163 | 0.77 | ITGB3 (0.41) | ITGB3ITGA2B | |
| Bromide SCHEMBL11261498 | 0.77 | ITGB3 (0.41) | ITGB3ITGA2B | |
| SCHEMBL30966230 | 0.76 | GNAO1 (0.34) | KDM1AMAOB | |
| SCHEMBL6621385 | 0.74 | ITGB3 (0.41) | ADRA2CITGB3ITGA2B | |
| SCHEMBL30984827 | 0.74 | APLNR (0.34) | — | |
| SCHEMBL2544949 | 0.73 | ITGB3 (0.41) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4606803-A1 | KRAS G12D DEGRADATION AGENT, AND PREPARATION METHOD AND USE THEREFOR | Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. (CN) | 2025-08-27 | — | — | EP | disclosed |
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |