Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.40 |
| ▸ | MGLL | Q99685 | 5/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29201762 | 1.00 | HSD11B1 (0.40) | HSD11B1MGLLPDE4BHTR1AFAAH | |
| SCHEMBL30995326 | 0.89 | DDB1 (0.42) | HSD11B1MEN1KMT2A | |
| SCHEMBL29201772 | 0.89 | HSD11B1 (0.39) | HSD11B1MGLL | |
| SCHEMBL30066197 | 0.87 | PDE4B (0.46) | HSD11B1MGLLPDE4BHTR1AFAAH | |
| SCHEMBL24670709 | 0.87 | PDE4B (0.46) | HSD11B1MGLLPDE4BHTR1AFAAH | |
| SCHEMBL30864000 | 0.86 | NR3C1 (0.41) | HSD11B1 | |
| SCHEMBL29201735 | 0.86 | NR3C1 (0.41) | HSD11B1 | |
| SCHEMBL24670711 | 0.85 | HSD11B1 (0.43) | HSD11B1MGLLFAAHMEN1KMT2A | |
| SCHEMBL29201724 | 0.83 | HTR1A (0.38) | HSD11B1MGLLHTR1A | |
| SCHEMBL24671840 | 0.82 | HSD11B1 (0.39) | HSD11B1MGLLPDE4BFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |