Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30864097 | 0.91 | GPR119 (0.39) | GPR119KMT2AMEN1PDK1PDK2 | |
| SCHEMBL29201756 | 0.91 | KMT2A (0.37) | KMT2A | |
| SCHEMBL31677332 | 0.88 | MGLL (0.34) | KMT2A | |
| SCHEMBL29892557 | 0.88 | GPR119 (0.43) | GPR119KMT2AMEN1PDK1PDK2 | |
| SCHEMBL31024364 | 0.88 | MEN1 (0.42) | GPR119KMT2AMEN1PDK1PDK2 | |
| SCHEMBL27124609 | 0.88 | MEN1 (0.42) | GPR119KMT2AMEN1PDK1PDK2 | |
| SCHEMBL27137466 | 0.85 | GPR119 (0.41) | GPR119KMT2AMEN1PDK1PDK2 | |
| SCHEMBL31677220 | 0.85 | MEN1 (0.41) | GPR119KMT2AMEN1PDK1PDK2 | |
| SCHEMBL23123648 | 0.84 | CNR1 (0.43) | GPR119KMT2AMEN1PDK1PDK2 | |
| SCHEMBL31161308 | 0.84 | CNR1 (0.43) | GPR119KMT2AMEN1PDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |