Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 8/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30204864 | 0.82 | HCAR3 (0.39) | HCAR3ALDH1A1SLC22A12PTGER4CSNK2A1 | |
| SCHEMBL6947602 | 0.77 | PTGER4 (0.43) | SSTR4ALDH1A1PTGER4HDAC3HDAC1 | |
| SCHEMBL12800752 | 0.74 | EPHX2 (0.45) | ALDH1A1PTGER4HDAC3HDAC1HDAC2 | |
| SCHEMBL23535658 | 0.73 | HCAR3 (0.36) | HCAR3SLC22A12CSNK2A1TNKSTNKS2 | |
| SCHEMBL30159550 | 0.73 | HCAR3 (0.36) | HCAR3SLC22A12CSNK2A1TNKSTNKS2 | |
| SCHEMBL30204313 | 0.73 | ALDH1A1 (0.38) | ALDH1A1PTGER4CSNK2A1 | |
| SCHEMBL4656671 | 0.72 | MLYCD (0.42) | SSTR4HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL13984783 | 0.72 | HDAC1 (0.49) | ALDH1A1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6944148 | 0.71 | HCAR3 (0.47) | HCAR3ALDH1A1 | |
| SCHEMBL6944145 | 0.71 | HCAR3 (0.47) | HCAR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858877-A | C-linked inhibitors of ENL/AF9 YEATS | 桥梁药品有限公司 | 2024-04-09 | — | — | CN | disclosed |