Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5388688 | 1.00 | MEN1 (0.62) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL5388684 | 1.00 | MEN1 (0.62) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL6568868 | 0.77 | GAA (0.45) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL6568870 | 0.77 | GAA (0.45) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL14159163 | 0.74 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL12416661 | 0.74 | NFE2L2 (0.63) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL7269602 | 0.73 | MEN1 (0.51) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL7269599 | 0.73 | MEN1 (0.51) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL28964169 | 0.72 | MEN1 (0.67) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL12416609 | 0.72 | MEN1 (0.67) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024064080-A1 | STAT6 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-03-28 | — | — | WO | claimed |
| WO-2024064080-A1 | STAT6 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-03-28 | — | — | WO | disclosed |