Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | WNT1 | P04628 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24810236 | 1.00 | MAPK1 (0.41) | MAPK1RAD52CYP1A2HPGDALDH1A1 | |
| SCHEMBL30848774 | 0.81 | GABRA1 (0.33) | MAPK1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL30164446 | 0.80 | EGLN1 (0.34) | MAPK1SMN1; SMN2TLR8TLR7KDM4E | |
| SCHEMBL24811771 | 0.80 | EGLN1 (0.34) | MAPK1SMN1; SMN2TLR8TLR7KDM4E | |
| SCHEMBL30164490 | 0.77 | KDM4E (0.40) | RAD52HRH4KDM4EGAA | |
| SCHEMBL24810572 | 0.77 | KDM4E (0.40) | RAD52HRH4KDM4EGAA | |
| SCHEMBL24813079 | 0.76 | MEN1 (0.36) | MAPK1ALDH1A1SMN1; SMN2KDM4EEGLN1 | |
| SCHEMBL30164468 | 0.76 | MEN1 (0.36) | MAPK1ALDH1A1SMN1; SMN2KDM4EEGLN1 | |
| SCHEMBL24813085 | 0.75 | ADORA2B (0.39) | — | |
| SCHEMBL30865616 | 0.75 | ADORA2B (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916232-A | Heterocyclic EGFR inhibitors for the treatment of cancer | 缆图药品公司 | 2024-04-19 | — | — | CN | disclosed |