Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 4/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.31 |
| ▸ | PRKCG | P05129 | 2/20 | 0.31 |
| ▸ | PRKCB | P05771 | 2/20 | 0.31 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
| ▸ | PRKCH | P24723 | 2/20 | 0.31 |
| ▸ | PRKCI | P41743 | 2/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.31 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11552985 | 0.80 | CTDSP1 (0.50) | CTDSP1APOBEC3AAPOBEC3GPOLBMAPT | |
| Hydrochloric Acid SCHEMBL11554319 | 0.78 | CTDSP1 (0.49) | CTDSP1APOBEC3AAPOBEC3GPOLBMAPT | |
| Hydrochloric Acid SCHEMBL9635896 | 0.77 | CTDSP1 (0.51) | CTDSP1APOBEC3AAPOBEC3GPOLBMAPT | |
| SCHEMBL19164699 | 0.74 | CTDSP1 (0.44) | CTDSP1APOBEC3AAPOBEC3GPOLBMAPT | |
| SCHEMBL19410338 | 0.68 | CTDSP1 (0.47) | CTDSP1APOBEC3AAPOBEC3GPOLBKMT2A | |
| SCHEMBL19420726 | 0.67 | CTDSP1 (1.00) | CTDSP1APOBEC3AAPOBEC3GPOLBMAPT | |
| SCHEMBL9118629 | 0.66 | CTDSP1 (0.37) | CTDSP1APOBEC3AAPOBEC3GPOLBMAPT | |
| SCHEMBL19420728 | 0.65 | CTDSP1 (0.41) | CTDSP1APOBEC3AAPOBEC3GPOLBMAPT | |
| Hydrochloric Acid SCHEMBL3759338 | 0.65 | CTDSP1 (0.36) | CTDSP1APOBEC3AAPOBEC3GPOLBMAPT | |
| SCHEMBL11338454 | 0.65 | THRB (0.53) | CTDSP1APOBEC3AAPOBEC3GPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917402-A | Isoindolylamide compound, and pharmaceutical composition and application thereof | 暨南大学 | 2024-04-23 | — | — | CN | disclosed |