Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118629 | 0.98 | CTDSP1 (0.37) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| SCHEMBL19164699 | 0.84 | CTDSP1 (0.44) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| Hydrochloric Acid SCHEMBL11554319 | 0.84 | CTDSP1 (0.49) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| Hydrochloric Acid SCHEMBL9635896 | 0.82 | CTDSP1 (0.51) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| SCHEMBL11552985 | 0.81 | CTDSP1 (0.50) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| Hydrochloric Acid SCHEMBL295168 | 0.80 | THRB (0.51) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| Hydrochloric Acid SCHEMBL11552155 | 0.78 | CTDSP1 (0.35) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| SCHEMBL11338454 | 0.77 | THRB (0.53) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| SCHEMBL13770474 | 0.70 | ALDH1A1 (0.33) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 | |
| SCHEMBL19410338 | 0.68 | CTDSP1 (0.47) | CTDSP1APOBEC3AAPOBEC3GPOLBPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406837-B1 | Cationic polysaccharides and reagents for their preparation | NAT STARCH CHEM INVEST (US) | 1995-10-18 | — | — | EP | claimed |
| US-5227481-A | Cationic polysaccharides and reagents for their preparation | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1993-07-13 | — | — | US | claimed |
| EP-0406837-A2 | Cationic polysaccharides and reagents for their preparation | National Starch and Chemical Investment Holding Corporation (US) | 1991-01-09 | — | — | EP | claimed |
| EP-1934263-B1 | NOVEL QUATERNARY POLYMERS | ARCHIMEDES DEV LTD (GB) | 2013-05-29 | — | — | EP | disclosed |
| US-7838643-B2 | Quaternary polymers | ARCHIMEDES DEVELOPMENT LIMITED (GB) | 2010-11-23 | — | — | US | disclosed |
| US-20090118480-A1 | Novel Quaternary Polymers | FENNOPHARMA OY (FI) | 2009-05-07 | — | — | US | disclosed |
| EP-1934263-A1 | NOVEL QUATERNARY POLYMERS | Fennopharma OY (FI) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007034032-A1 | NOVEL QUATERNARY POLYMERS | FENNOPHARMA OY (FI) | 2007-03-29 | — | — | WO | disclosed |
| US-6193843-B1 | PREPARED BY REACTING A POLYSACCHARIDE WITH A POLYCATIONIC REAGENT HAVING ONE POLYSACCHARIDE REACTIVE GROUP AND AT LEAST TWO CATIONIC GROUPS; SUITABLE REAGENTS INCLUDE POLYCATIONIC ALKYL, ARYL, ALKARYL, CYCLOALIPHATIC, OR HETEROCYCLIC AMINES | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION | 2001-02-27 | — | — | US | disclosed |
| EP-0406837-B1 | Cationic polysaccharides and reagents for their preparation | NAT STARCH CHEM INVEST (US) | 1995-10-18 | — | — | EP | disclosed |
| US-5349089-A | N-/3-/haloethylethyl/aminopropyl/N,N,N-trimethylammonium salt | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1994-09-20 | — | — | US | disclosed |
| US-5227481-A | Cationic polysaccharides and reagents for their preparation | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1993-07-13 | — | — | US | disclosed |
| EP-0406837-A2 | Cationic polysaccharides and reagents for their preparation | National Starch and Chemical Investment Holding Corporation (US) | 1991-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118480-A1 | Novel Quaternary Polymers | CHIA, HDAC5, ALG1 | CTDSP1 376/4885APOBEC3A 3072/4885APOBEC3G 2763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.