Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.54 |
| ▸ | F2R | P25116 | 1/20 | 0.54 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.54 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26623324 | 1.00 | MTNR1A (0.57) | MTNR1AMTNR1BRAB9ANPC1POLB | |
| SCHEMBL9842887 | 0.89 | F2R (0.68) | MTNR1AMTNR1BRAB9ANPC1GAA | |
| SCHEMBL17680553 | 0.87 | POLB (0.58) | MTNR1AMTNR1BRAB9APOLBNR4A1 | |
| SCHEMBL9429773 | 0.87 | NPC1 (0.55) | RAB9ANPC1POLBGAAALDH1A1 | |
| SCHEMBL10294097 | 0.87 | MTNR1B (0.58) | MTNR1AMTNR1BRAB9APOLBNR4A1 | |
| SCHEMBL23060408 | 0.86 | F2R (0.59) | MTNR1AMTNR1BRAB9ANPC1ALDH1A1 | |
| SCHEMBL26623397 | 0.85 | HDAC3 (0.60) | MTNR1BRAB9ANPC1GAAALDH1A1 | |
| SCHEMBL8605571 | 0.85 | NPC1 (0.53) | RAB9ANPC1POLBGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL20568958 | 0.84 | ALDH1A1 (0.54) | RAB9ANPC1POLBGAAALDH1A1 | |
| SCHEMBL13170081 | 0.83 | L3MBTL1 (0.64) | MTNR1AMTNR1BRAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917402-A | Isoindolylamide compound, and pharmaceutical composition and application thereof | 暨南大学 | 2024-04-23 | — | — | CN | disclosed |