Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | TP53 | P04637 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.63 |
| ▸ | ESR1 | P03372 | 4/20 | 0.62 |
| ▸ | PGR | P06401 | 2/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.62 |
| ▸ | AR | P10275 | 2/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722468 | 0.91 | MAPT (0.65) | LMNAKMT2ACYP3A4MEN1ALOX15 | |
| SCHEMBL9010987 | 0.91 | ESR1 (0.70) | LMNAKMT2ACYP3A4MEN1ALOX15 | |
| SCHEMBL26659960 | 0.89 | LMNA (0.76) | LMNAKMT2ACYP3A4MEN1ALOX15 | |
| SCHEMBL12180360 | 0.89 | LMNA (0.76) | LMNAKMT2ACYP3A4MEN1ALOX15 | |
| SCHEMBL308659 | 0.89 | LMNA (0.76) | LMNAKMT2ACYP3A4MEN1ALOX15 | |
| SCHEMBL8722555 | 0.88 | KMT2A (0.69) | LMNAKMT2ACYP3A4MEN1ALOX15 | |
| Estrapronicate SCHEMBL1133125 | 0.87 | MAPT (0.75) | LMNAKMT2ACYP3A4MEN1ALOX15 | |
| SCHEMBL10527381 | 0.84 | LMNA (0.49) | LMNAKMT2ACYP3A4MEN1ALOX15 | |
| SCHEMBL5152447 | 0.84 | CA2 (0.65) | LMNAKMT2ACYP3A4MEN1ALOX15 | |
| SCHEMBL3871356 | 0.83 | CA2 (0.73) | LMNAKMT2ACYP3A4MEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525727-A | ANALGESIC OR NARCOTIC ANTAGONIST | UNIVERSITY OF FLORIDA (US) | 1996-06-11 | — | — | US | disclosed |
| US-5187158-A | Sustained delivery of viricides | UNIVERSITY OF FLORIDA (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0256668-B1 | METHOD FOR TREATING MALE SEXUAL DYSFUNCTION | UNIVERSITY OF FLORIDA (US) | 1992-11-04 | — | — | EP | disclosed |
| US-5008257-A | Penicillin or cephalosporin antibiotics | UNIVERSITY OF FLORIDA (US) | 1991-04-16 | — | — | US | disclosed |
| US-4900837-A | Brain-specific drug delivery of steroid sex hormones cleaved from pyridinium carboxylates and dihydro-pyridine carboxylate precursors | UNIVERSITY OF FLORIDA (US) | 1990-02-13 | — | — | US | disclosed |
| US-4880921-A | Brain-specific drug delivery | UNIVERSITY OF FLORIDA (US) | 1989-11-14 | — | — | US | disclosed |
| US-4863911-A | Method for treating male sexual dysfunction | UNIVERSITY OF FLORIDA (US) | 1989-09-05 | — | — | US | disclosed |
| US-4824850-A | DIHYDROPYRIDINE-PYRIDINIUM SALT REDOX CARRIER | UNIVERSITY OF FLORIDA (US) | 1989-04-25 | — | — | US | disclosed |
| EP-0220844-A2 | Use of estrogen-dihydropyridine compounds for weight control | UNIVERSITY OF FLORIDA (US) | 1987-05-06 | — | — | EP | disclosed |
| US-4617298-A | STEROIDS | UNIVERSITY OF FLORIDA (US) | 1986-10-14 | — | — | US | disclosed |