Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13735446 | 0.82 | TDP1 (0.49) | TDP1ACMSDALDH1A1MAPTLMNA | |
| SCHEMBL30868397 | 0.79 | ALDH1A1 (0.51) | TDP1ACMSDALDH1A1MAPTLMNA | |
| SCHEMBL9083468 | 0.79 | ACMSD (0.56) | TDP1ACMSDALDH1A1MAPTLMNA | |
| SCHEMBL13736939 | 0.78 | TDP1 (0.47) | TDP1ACMSDALDH1A1MAPTLMNA | |
| SCHEMBL20150205 | 0.75 | TDP1 (0.45) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL6181269 | 0.75 | ALDH1A1 (0.50) | TDP1ACMSDALDH1A1MAPTLMNA | |
| SCHEMBL13735705 | 0.75 | HDAC2 (0.46) | ACMSDALDH1A1NPSR1HDAC1HDAC2 | |
| SCHEMBL2573156 | 0.75 | THRB (0.49) | ACMSDALDH1A1MAPTLMNAHTT | |
| SCHEMBL17736221 | 0.75 | TDP1 (0.60) | TDP1ACMSDALDH1A1MAPTLMNA | |
| SCHEMBL25447049 | 0.74 | MAPT (0.49) | ACMSDALDH1A1MAPTHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028169-A1 | NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2024-02-08 | — | — | WO | disclosed |