Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 11/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181269 | 0.96 | ALDH1A1 (0.50) | ALDH1A1LMNACHEK1SIRT6TDP1 | |
| SCHEMBL6177383 | 0.86 | PDGFRB (0.46) | ALDH1A1LMNATDP1PDGFRBPDGFRA | |
| SCHEMBL309803 | 0.82 | CHEK1 (0.46) | ALDH1A1LMNACHEK1SIRT6TDP1 | |
| SCHEMBL522135 | 0.81 | QDPR (0.62) | ALDH1A1LMNACHEK1SIRT6 | |
| SCHEMBL2208088 | 0.81 | ADRA2A (0.46) | ALDH1A1LMNACHEK1SIRT6TDP1 | |
| SCHEMBL11224598 | 0.81 | CHEK1 (0.61) | ALDH1A1LMNACHEK1SIRT6TDP1 | |
| SCHEMBL15993325 | 0.80 | QDPR (0.63) | ALDH1A1LMNACHEK1SIRT6MAPT | |
| SCHEMBL30868525 | 0.80 | SIRT6 (0.49) | CHEK1SIRT6TDP1PDGFRBPDGFRA | |
| SCHEMBL2201835 | 0.80 | SIRT6 (0.53) | ALDH1A1LMNACHEK1SIRT6TDP1 | |
| Hydrochloric Acid SCHEMBL521660 | 0.80 | QDPR (0.61) | ALDH1A1LMNACHEK1SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028169-A1 | NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2024-02-08 | — | — | WO | disclosed |