Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | BCL6 | P41182 | 1/20 | 0.37 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31125155 | 0.89 | LMNA (0.48) | ALDH1A1LMNAVCAM1GAASMN1; SMN2 | |
| SCHEMBL26927888 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAVCAM1GAASMN1; SMN2 | |
| SCHEMBL26130709 | 0.78 | ALDH1A1 (0.47) | ALDH1A1LMNAGAAMAPTMEN1 | |
| SCHEMBL30868330 | 0.75 | HTT (0.51) | ALDH1A1LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL30868472 | 0.75 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL30868341 | 0.75 | ALDH1A1 (0.52) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL25447115 | 0.74 | ALDH1A1 (0.46) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL8140554 | 0.74 | VCAM1 (0.60) | ALDH1A1LMNAVCAM1GAASMN1; SMN2 | |
| SCHEMBL2573156 | 0.72 | THRB (0.49) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL7023145 | 0.72 | VCAM1 (0.57) | ALDH1A1LMNAVCAM1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028169-A1 | NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2024-02-08 | — | — | WO | disclosed |