Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5274044 | 0.87 | BRD4 (0.34) | — | |
| Hydrochloric Acid SCHEMBL272104 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL5476875 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL6895143 | 0.82 | BRD4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL5583996 | 0.79 | BRD4 (0.32) | — | |
| Hydrochloric Acid SCHEMBL6886332 | 0.78 | BRD4 (0.34) | — | |
| Hydrochloric Acid SCHEMBL7199314 | 0.77 | ALDH1A1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL6885762 | 0.77 | RXRA (0.30) | — | |
| Hydrochloric Acid SCHEMBL6894555 | 0.77 | DRD2 (0.36) | — | |
| SCHEMBL7161704 | 0.77 | BRD4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576642-A2 | PROCESS FOR PREPARING A SUPPORTED CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, THE CATALYST SYSTEM AND ITS USE | Basell Polyolefine GmbH (DE) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011147573-A2 | PROCESS FOR PREPARING A SUPPORTED CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, THE CATALYST SYSTEM AND ITS USE | BASELL POLYOLEFINE GMBH (DE) | 2011-12-01 | — | — | WO | disclosed |
| US-7795167-B2 | Cyclopentadienyl complexes of group 6 substituted by silyl halides | BASELL POLYOLEFINE GMBH (DE) | 2010-09-14 | — | — | US | disclosed |
| US-20080097053-A1 | Cyclopentadienyl Complexes Of Group 6 Substituted By Silyl Halides | BASELL POLYOLEFINE GMBH (DE) | 2008-04-24 | — | — | US | disclosed |