Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 5/20 | 0.78 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | ATM | Q13315 | 1/20 | 0.76 |
| ▸ | HTT | P42858 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | BRAF | P15056 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16696529 | 0.89 | HSP90AA1 (0.74) | P4HBHSP90AA1KMT2AATMHTT | |
| SCHEMBL14652565 | 0.88 | P4HB (0.79) | P4HBHSP90AA1KMT2AATMHTT | |
| SCHEMBL29549198 | 0.87 | KMT2A (1.00) | P4HBHSP90AA1KMT2AATMHTT | |
| SCHEMBL9962883 | 0.87 | KMT2A (1.00) | P4HBHSP90AA1KMT2AATMHTT | |
| SCHEMBL1700908 | 0.86 | P4HB (0.98) | P4HBHSP90AA1KMT2AATMHTT | |
| SCHEMBL16696547 | 0.85 | P4HB (0.79) | P4HBHSP90AA1KMT2AATMHTT | |
| SCHEMBL18313865 | 0.80 | MCL1 (0.79) | P4HBHSP90AA1KMT2AATMHTT | |
| SCHEMBL14680236 | 0.79 | P4HB (0.69) | P4HBHSP90AA1KMT2AATMHTT | |
| SCHEMBL9960186 | 0.78 | PPP1CA (0.79) | P4HBHSP90AA1KMT2AATMHTT | |
| SCHEMBL12436071 | 0.78 | ALDH1A1 (0.76) | P4HBHSP90AA1KMT2AATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260103444-A1 | 8-HYDROXYQUINOLINE COMPOUND AND USE THEREOF | UNIV OSAKA (JP) | 2026-04-16 | — | — | US | disclosed |
| EP-4599832-A1 | 8-HYDROXYQUINOLINE COMPOUND AND USE THEREOF | OSAKA UNIVERSITY (JP) | 2025-08-13 | — | — | EP | disclosed |
| CN-119968204-A | 8-Hydroxyquinoline compound and use thereof | 国立大学法人大阪大学 | 2025-05-09 | — | — | CN | disclosed |
| WO-2024075815-A1 | 8-HYDROXYQUINOLINE COMPOUND AND USE THEREOF | 国立大学法人大阪大学 | 2024-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260103444-A1 | 8-HYDROXYQUINOLINE COMPOUND AND USE THEREOF | MYLK2, MYLK, ATP2A1 | P4HB 4390/4885HSP90AA1 2607/4885KMT2A 1971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.