SCHEMBL30869381

SCHEMBL30869381

Brc1ccc2c(c1)Oc1cc(Br)ccc1N2CCCCN1CC2COCC(C2)C1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 4/20 0.34
SMPD1 P17405 1/20 0.33
SIGMAR1 Q99720 1/20 0.32
AHR P35869 1/20 0.32
DRD2 P14416 1/20 0.31
HTR2A P28223 1/20 0.31
HTR7 P34969 1/20 0.31
HTR6 P50406 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869517 0.99 PIM1 (0.34) PIM1SMPD1SIGMAR1AHRDRD2
SCHEMBL30869398 0.98 SMPD1 (0.35) PIM1SMPD1SIGMAR1AHRDRD2
SCHEMBL30869423 0.93 PIM1 (0.40) PIM1AHRDRD2HTR2AHTR7
SCHEMBL30869449 0.90 TSHR (0.35) PIM1
SCHEMBL30869482 0.88 PIM1 (0.32) PIM1
SCHEMBL30869904 0.88 PIM1 (0.32) PIM1
SCHEMBL30869659 0.86 PIM1 (0.32) PIM1
SCHEMBL30869404 0.80 KMT2A (0.33)
SCHEMBL30869533 0.80
SCHEMBL30869534 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 PIM1 4177/4885SMPD1 261/4885SIGMAR1 182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.