SCHEMBL30869643

SCHEMBL30869643

CC(=O)N1c2c(C)cccc2Oc2cccc(C)c21

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
P2RX4 Q99571 8/20 0.44
ALDH1A1 P00352 3/20 0.39
P2RX1 P51575 1/20 0.39
NOTUM Q6P988 1/20 0.39
TP53 P04637 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3451033 0.73 SMN1; SMN2 (0.75) MAPTSMN1; SMN2NPSR1P2RX4P2RX1
SCHEMBL22600935 0.69 ALDH1A1 (0.34) NPSR1P2RX4ALDH1A1
SCHEMBL30869549 0.69 MAPT (0.37) MAPTSMN1; SMN2NPSR1P2RX4P2RX1
Acetic Acid SCHEMBL10626222 0.66 P2RX4 (0.47) MAPTSMN1; SMN2NPSR1P2RX4
SCHEMBL23565774 0.64
Acetic Acid SCHEMBL29701132 0.64 ALDH1A1 (0.46) SMN1; SMN2ALDH1A1
Acetamide SCHEMBL28954498 0.64 ATM (0.54) MAPTSMN1; SMN2NPSR1P2RX4
SCHEMBL3423393 0.64 AHR (0.43) ALDH1A1TP53HTT
SCHEMBL25137434 0.64 ALDH1A1 (0.34) ALDH1A1TP53HTT
SCHEMBL24390084 0.63 P2RX4 (0.40) MAPTSMN1; SMN2NPSR1P2RX4P2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 MAPT 2165/4885SMN1; SMN2 1915/4885NPSR1 2451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.