SCHEMBL30869684

SCHEMBL30869684

Cc1cc2c(cc1-c1ccc3[nH]ncc3c1)Oc1cc(-c3ccc4[nH]ncc4c3)cnc1N2CCCCN1C[C@@H]2C[C@H]1CO2

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 4/20 0.40
KCNH2 Q12809 1/20 0.39
WNT1 P04628 4/20 0.35
GSK3B P49841 4/20 0.35
DYRK1A Q13627 4/20 0.35
LRRK2 Q5S007 1/20 0.33
TRPA1 O75762 1/20 0.33
KRAS P01116 1/20 0.33
BRAF P15056 1/20 0.33
ROCK2 O75116 2/20 0.33
ROCK1 Q13464 2/20 0.33
MAP3K11 Q16584 1/20 0.33
TNIK Q9UKE5 1/20 0.33
MAPK14 Q16539 1/20 0.32
USP30 Q70CQ3 1/20 0.32
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32
S1PR1 P21453 1/20 0.31
KIF11 P52732 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869784 1.00 CHRNA7 (0.40) CHRNA7KCNH2WNT1GSK3BDYRK1A
SCHEMBL30869744 0.99 CHRNA7 (0.39) CHRNA7KCNH2WNT1GSK3BDYRK1A
SCHEMBL30869564 0.99 CHRNA7 (0.39) CHRNA7KCNH2WNT1GSK3BDYRK1A
SCHEMBL30869437 0.92 CHRNA7 (0.38) CHRNA7KCNH2WNT1GSK3BDYRK1A
SCHEMBL30869688 0.92 CHRNA7 (0.38) CHRNA7KCNH2WNT1GSK3BDYRK1A
SCHEMBL30869764 0.91 CHRNA7 (0.42) CHRNA7KCNH2WNT1GSK3BDYRK1A
SCHEMBL30869736 0.91 CHRNA7 (0.42) CHRNA7KCNH2WNT1GSK3BDYRK1A
SCHEMBL30869632 0.90 CHRNA7 (0.41) CHRNA7KCNH2WNT1GSK3BDYRK1A
SCHEMBL30869791 0.90 CHRNA7 (0.43) CHRNA7KCNH2WNT1GSK3BDYRK1A
SCHEMBL30869440 0.90 CHRNA7 (0.43) CHRNA7KCNH2WNT1GSK3BDYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 CHRNA7 1850/4885KCNH2 851/4885WNT1 3840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.