SCHEMBL30869757

SCHEMBL30869757

FC(F)(F)CN1c2ccc(Br)cc2Oc2cc(Br)ccc21

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.44
PIM1 P11309 3/20 0.33
CUL4A Q13619 1/20 0.32
ACHE P22303 1/20 0.30
ATM Q13315 1/20 0.30
CA12 O43570 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23573065 0.77 AHR (0.48) AHRPIM1CUL4AACHEATM
SCHEMBL31443280 0.77 AHR (0.48) AHRPIM1CUL4AACHEATM
SCHEMBL32685459 0.75 AHR (0.47) AHRPIM1CUL4AACHEATM
SCHEMBL9980173 0.74 TSHR (0.35) ATMLMNAMAPTHTT
SCHEMBL30869472 0.72 AHR (0.44) AHRPIM1CUL4AACHEATM
SCHEMBL13308132 0.71 AHR (0.42) AHRPIM1CUL4A
SCHEMBL31314370 0.71 ALDH1A1 (0.44) AHRPIM1LMNAMAPT
SCHEMBL2705505 0.71 SLC1A3 (0.32) PIM1
SCHEMBL15607139 0.70 AHR (0.50) AHRPIM1ATMMAPT
SCHEMBL30869546 0.70 MAPT (0.51) AHRPIM1CUL4AATMCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 AHR 4553/4885PIM1 4177/4885CUL4A 3034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.