SCHEMBL30869811

SCHEMBL30869811

FC1(F)CN(CCN2c3ccc(Br)cc3Oc3cc(Br)ccc32)CCO1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 3/20 0.41
MEN1 O00255 1/20 0.37
TDP2 O95551 1/20 0.37
CFTR P13569 1/20 0.37
CASP6 P55212 1/20 0.37
KMT2A Q03164 1/20 0.37
HKDC1 Q2TB90 1/20 0.37
GOPC Q9HD26 1/20 0.37
CNR1 P21554 1/20 0.34
PKM P14618 1/20 0.34
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.32
AHR P35869 1/20 0.32
KDM1A O60341 1/20 0.32
ABL1 P00519 1/20 0.31
RIN1 Q13671 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA1B P35368 1/20 0.31
DRD2 P14416 1/20 0.31
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869597 0.82 PIM1 (0.50) PIM1MEN1TDP2CFTRCASP6
SCHEMBL30869737 0.74 KDM1A (0.51) PIM1MEN1TDP2CFTRCASP6
SCHEMBL30869712 0.74 PIM1 (0.41) PIM1MEN1TDP2CFTRCASP6
SCHEMBL30869638 0.73 PIM1 (0.39) PIM1MEN1TDP2CFTRCASP6
SCHEMBL30869377 0.73 PIM1 (0.39) PIM1MEN1TDP2CFTRCASP6
SCHEMBL30869733 0.72 PIM1 (0.40) PIM1MEN1TDP2CFTRCASP6
SCHEMBL30869458 0.72 TSHR (0.56) PIM1MEN1TDP2CFTRCASP6
SCHEMBL32685459 0.72 AHR (0.47) PIM1MEN1KMT2APKMLMNA
SCHEMBL30869590 0.70 PIM1 (0.45) PIM1MEN1TDP2CFTRCASP6
SCHEMBL30869472 0.70 AHR (0.44) PIM1MEN1KMT2APKMTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed