Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 4/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29657364 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MEN1LMNAKMT2ASLC1A3 | |
| SCHEMBL21635774 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MEN1LMNAKMT2ASLC1A3 | |
| SCHEMBL882883 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MEN1LMNAKMT2ASLC1A3 | |
| SCHEMBL16658841 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MEN1LMNAKMT2ASLC1A3 | |
| SCHEMBL1415449 | 0.79 | NOD1 (0.45) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL2172011 | 0.78 | — | — | |
| SCHEMBL1604327 | 0.78 | — | — | |
| SCHEMBL7450904 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL818702 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MEN1LMNAKMT2AFOLH1 | |
| SCHEMBL818701 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MEN1LMNAKMT2AFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117925548-A | Fe (II)/alpha-KG dioxygenase mutant for synthesizing 5-hydroxy-L-homoleucine and application thereof | 江南大学 | 2024-04-26 | — | — | CN | disclosed |