⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3065739 | 0.90 | PGD (0.30) | — | |
| SCHEMBL3080212 | 0.84 | PGD (0.31) | — | |
| SCHEMBL3077340 | 0.84 | PGD (0.31) | — | |
| SCHEMBL3061747 | 0.84 | TLR2 (0.32) | — | |
| SCHEMBL3074259 | 0.84 | TLR2 (0.32) | — | |
| SCHEMBL3081598 | 0.77 | DDAH1 (0.34) | — | |
| SCHEMBL3070733 | 0.72 | MET (0.39) | — | |
| SCHEMBL20875793 | 0.69 | DNM1 (0.40) | — | |
| SCHEMBL20875737 | 0.69 | DNM1 (0.40) | — | |
| SCHEMBL20875836 | 0.69 | DNM1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790926-B2 | Alpha, omega-difunctional aldaramides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-09-07 | — | — | US | disclosed |
| US-7351862-B2 | Alpha, omega-difunctional aldaramides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-04-01 | — | — | US | disclosed |
| EP-1853554-A2 | ALPHA, OMEGA-DIFUNCTIONAL ALDARAMIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-11-14 | — | — | EP | disclosed |
| US-20060258886-A1 | Alpha, omega-difuctional aldaramides | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| WO-2006091902-A2 | ALPHA, OMEGA-DIFUNCTIONAL ALDARAMIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-08-31 | — | — | WO | disclosed |