Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13332664 | 0.87 | GPR119 (0.44) | LMNASMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL1979197 | 0.87 | GPR119 (0.44) | LMNASMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL26685092 | 0.86 | KMT2A (0.43) | LMNASMARCA2SMARCA4OPRM1OPRK1 | |
| SCHEMBL2370569 | 0.85 | MMP8 (0.41) | LMNASMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL27883965 | 0.81 | MMP8 (0.41) | LMNASMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL27273649 | 0.77 | ALDH1A1 (0.41) | LMNASMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL23027132 | 0.76 | FFAR2 (0.56) | LMNASMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL11062117 | 0.76 | FFAR2 (0.56) | LMNASMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL29272210 | 0.74 | PTGS1 (0.47) | SMARCA2SMARCA4OPRM1OPRK1KCNH2 | |
| SCHEMBL27481923 | 0.73 | AKR1C3 (0.48) | LMNASMN1; SMN2ALDH1A1MAPTSMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940404-A | Tricyclic compounds as Cbl-b inhibitors | 海南先声再明医药股份有限公司 | 2024-04-26 | — | — | CN | disclosed |