Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | TNKS | O95271 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | BCL9 | O00512 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30014987 | 0.92 | MGLL (0.39) | MGLLTSHRHSD11B1TNKSPARP1 | |
| SCHEMBL27123888 | 0.92 | MGLL (0.39) | MGLLTSHRHSD11B1TPSAB1TPSD1 | |
| SCHEMBL31697885 | 0.92 | MGLL (0.39) | MGLLTSHRHSD11B1TPSAB1TPSD1 | |
| SCHEMBL30014221 | 0.88 | ITGB3 (0.38) | MGLLTSHRHSD11B1TPSAB1TPSD1 | |
| SCHEMBL27125679 | 0.88 | ITGB3 (0.38) | MGLLTSHRHSD11B1TPSAB1TPSD1 | |
| SCHEMBL27124624 | 0.87 | MGLL (0.41) | MGLLTSHRHSD11B1TPSAB1TPSD1 | |
| SCHEMBL30872318 | 0.86 | ENPP2 (0.40) | — | |
| SCHEMBL31677332 | 0.86 | MGLL (0.34) | MGLLTSHRHSD11B1CCR3SMYD3 | |
| SCHEMBL31255494 | 0.86 | TPSAB1 (0.42) | MGLLTSHRHSD11B1TPSAB1TPSD1 | |
| SCHEMBL27137557 | 0.84 | LSS (0.35) | MGLLTSHRHSD11B1TPSAB1TPSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024083255-A1 | BENZYL OR THIENYLMETHYLENE-SUBSTITUTED AMINOQUINAZOLINE DERIVATIVE AND USE THEREOF AS SOS1 DEGRADATION AGENT | 上海领泰生物医药科技有限公司 | 2024-04-25 | — | — | WO | disclosed |