Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.38 |
| ▸ | HTR7 | P34969 | 10/20 | 0.38 |
| ▸ | DPP4 | P27487 | 8/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874966 | 0.78 | POLB (0.40) | HTR1AHTR7DPP4 | |
| SCHEMBL30874837 | 0.69 | DPP4 (0.39) | HTR1AHTR7DPP4 | |
| SCHEMBL30874924 | 0.68 | HTR1A (0.39) | HTR1AHTR7DPP4 | |
| SCHEMBL30874951 | 0.67 | DPP4 (0.43) | HTR1AHTR7DPP4 | |
| SCHEMBL30874864 | 0.66 | VNN1 (0.47) | HTR1AHTR7DPP4 | |
| SCHEMBL30874955 | 0.66 | DPP4 (0.42) | HTR1AHTR7DPP4 | |
| SCHEMBL15856041 | 0.66 | DPP4 (0.44) | HTR1AHTR7DPP4 | |
| SCHEMBL30874829 | 0.65 | GFER (0.45) | HTR1AHTR7DPP4 | |
| SCHEMBL30874846 | 0.65 | DPP4 (0.47) | HTR1AHTR7DPP4 | |
| SCHEMBL30874926 | 0.65 | DPP4 (0.44) | HTR1AHTR7DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |