SCHEMBL30875722

SCHEMBL30875722

CC(C)C12C(=O)OC(=O)C1C2C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.36
ACE P12821 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23979209 0.72 MEN1 (0.32) TSHR
SCHEMBL910568 0.58 TP53 (0.50) TSHR
SCHEMBL911568 0.58 TP53 (0.50) TSHR
SCHEMBL13818245 0.58 GRM2 (0.32)
SCHEMBL19630999 0.57 TP53 (0.32) TSHR
SCHEMBL8677497 0.57 TP53 (0.32) TSHR
SCHEMBL7200169 0.57 MAPK1 (0.32) TSHR
SCHEMBL29259283 0.56 ALDH1A1 (0.34) TSHR
SCHEMBL3140773 0.55
SCHEMBL9804360 0.55 FFAR3 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113149968-B Compound serving as ketohexokinase inhibitor and application thereof 博济医药科技股份有限公司 2024-06-04 CN disclosed