Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30877459 | 0.79 | ALDH1A1 (0.45) | RAPGEF4L3MBTL1CA1CA2ALDH3A1 | |
| SCHEMBL30877496 | 0.76 | RAPGEF4 (0.48) | RAPGEF4L3MBTL1CA1CA2ALDH3A1 | |
| SCHEMBL30877518 | 0.75 | RAPGEF4 (0.49) | RAPGEF4L3MBTL1CA1CA2ALDH3A1 | |
| SCHEMBL7678499 | 0.73 | RAPGEF4 (0.56) | RAPGEF4L3MBTL1CA1CA2ALDH3A1 | |
| SCHEMBL30877247 | 0.71 | RAPGEF4 (0.51) | RAPGEF4L3MBTL1CA1CA2ALDH3A1 | |
| SCHEMBL30877269 | 0.71 | RAPGEF4 (0.48) | RAPGEF4L3MBTL1CA1CA2ALDH3A1 | |
| SCHEMBL25425550 | 0.70 | RAPGEF4 (0.50) | RAPGEF4L3MBTL1CA1CA2ALDH3A1 | |
| SCHEMBL3834757 | 0.70 | RAPGEF4 (0.65) | RAPGEF4L3MBTL1CA1CA2ALDH3A1 | |
| SCHEMBL21590225 | 0.70 | RAPGEF4 (0.52) | RAPGEF4L3MBTL1CA1CA2ALDH3A1 | |
| SCHEMBL28458237 | 0.70 | RAPGEF4 (0.52) | RAPGEF4L3MBTL1CA1CA2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |