Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 3/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678499 | 0.86 | RAPGEF4 (0.56) | RAPGEF4HTR6LMNACA1CA2 | |
| SCHEMBL21590225 | 0.85 | RAPGEF4 (0.52) | RAPGEF4HTR6LMNACA1CA2 | |
| SCHEMBL28453157 | 0.85 | HTR6 (0.58) | RAPGEF4HTR6CA1CA2L3MBTL1 | |
| SCHEMBL28456535 | 0.83 | RAPGEF4 (0.57) | RAPGEF4HTR6LMNACA1CA2 | |
| SCHEMBL28451886 | 0.83 | RAPGEF4 (0.61) | RAPGEF4HTR6PTGS2PTGS1CA1 | |
| SCHEMBL30041811 | 0.78 | HTR6 (0.53) | RAPGEF4HTR6LMNACA1CA2 | |
| SCHEMBL28074550 | 0.78 | RAPGEF4 (0.49) | RAPGEF4HTR6LMNACA1CA2 | |
| SCHEMBL5535689 | 0.78 | RAPGEF4 (0.61) | RAPGEF4CA1CA2PKML3MBTL1 | |
| SCHEMBL30427800 | 0.77 | HTR6 (0.52) | HTR6PTGS2LMNAPTGS1PKM | |
| SCHEMBL1156049 | 0.77 | LMNA (0.44) | PTGS2LMNATHRBPTGS1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111635349-B | Method for efficiently synthesizing polysubstituted pyrrole compound | 江苏大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-111635349-A | Method for efficiently synthesizing polysubstituted pyrrole compound | 江苏大学 | 2020-09-08 | — | — | CN | disclosed |