Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 3/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 3/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 4/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.33 |
| ▸ | CDK2 | P24941 | 3/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29285150 | 0.83 | DGAT1 (0.38) | DGAT1FLT3 | |
| SCHEMBL30690645 | 0.78 | IRAK4 (0.35) | BAZ2BBAZ2ASCN2ACECR2DGAT1 | |
| SCHEMBL30877396 | 0.77 | PGR (0.35) | BAZ2BBAZ2ASCN2ACECR2DGAT1 | |
| SCHEMBL14859280 | 0.77 | DGAT1 (0.39) | DGAT1CYP11B1CYP11B2CCNCCDK8 | |
| SCHEMBL29285168 | 0.76 | DGAT1 (0.42) | DGAT1LRRK2 | |
| SCHEMBL5654607 | 0.71 | KLKB1 (0.45) | DGAT1 | |
| SCHEMBL27282901 | 0.69 | BAZ2B (0.38) | BAZ2BBAZ2ADGAT1LRRK2RET | |
| SCHEMBL2129540 | 0.69 | DGAT1 (0.37) | DGAT1CYP11B1CYP11B2FLT3CCNC | |
| SCHEMBL18000647 | 0.69 | DGAT1 (0.35) | DGAT1CYP11B2 | |
| SCHEMBL8472530 | 0.68 | DGAT1 (0.39) | DGAT1CYP11B1CYP11B2FLT3LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |