Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALKBH1 | Q13686 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25254975 | 0.80 | KLKB1 (0.47) | KLKB1EGLN1DGAT1NPC1 | |
| SCHEMBL17222119 | 0.80 | KLKB1 (0.47) | KLKB1DGAT1NPC1 | |
| SCHEMBL23997682 | 0.80 | KLKB1 (0.47) | KLKB1DGAT1NPC1 | |
| SCHEMBL1858741 | 0.74 | DGAT1 (0.37) | KLKB1DGAT1 | |
| SCHEMBL2934571 | 0.73 | DGAT1 (0.36) | KLKB1DGAT1 | |
| SCHEMBL17222067 | 0.72 | KLKB1 (0.45) | KLKB1DGAT1NPC1 | |
| SCHEMBL12984274 | 0.71 | KLKB1 (0.41) | KLKB1DGAT1NPC1 | |
| SCHEMBL29977642 | 0.71 | KLKB1 (0.39) | KLKB1DGAT1NPC1 | |
| SCHEMBL30877441 | 0.71 | BAZ2B (0.38) | DGAT1 | |
| SCHEMBL4152078 | 0.69 | KLKB1 (0.37) | KLKB1DGAT1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674100-B2 | Inhibitors of C-FMS kinase | JANSSEN PHARMACEUTICA, N.V. (BE) | 2014-03-18 | — | — | US | disclosed |
| US-20070249649-A1 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249649-A1 | INHIBITORS OF C-FMS KINASE | FES, MUSK, FRK | KLKB1 1250/4885EGLN1 4405/4885DGAT1 3866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.