Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | GHSR | Q92847 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27185165 | 1.00 | OPRK1 (0.58) | OPRK1CYP3A4DRD3PDE4DSLC22A1 | |
| SCHEMBL7311633 | 0.91 | GABRG2 (0.54) | OPRK1CYP3A4DRD3PDE4DSLC22A1 | |
| SCHEMBL7309925 | 0.91 | GABRA3 (0.55) | OPRK1CYP3A4DRD3PDE4DSLC22A1 | |
| SCHEMBL7313844 | 0.91 | OPRK1 (0.60) | OPRK1CYP3A4DRD3PDE4DSLC22A1 | |
| SCHEMBL11379951 | 0.89 | OPRK1 (0.57) | OPRK1CYP3A4DRD3PDE4DSLC22A1 | |
| SCHEMBL5354151 | 0.88 | GABRA2 (0.54) | OPRK1GABRG2GABRB3GABRA3KCNH2 | |
| SCHEMBL1311112 | 0.88 | OPRK1 (0.63) | OPRK1CYP3A4DRD3PDE4DSLC22A1 | |
| SCHEMBL7315246 | 0.88 | OPRK1 (0.58) | OPRK1CYP3A4DRD3PDE4DSLC22A1 | |
| SCHEMBL7317914 | 0.87 | OPRK1 (0.62) | OPRK1CYP3A4DRD3PDE4DSLC22A1 | |
| SCHEMBL7307575 | 0.87 | GABRG2 (0.62) | OPRK1CYP3A4DRD3PDE4DSLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059669-A2 | IMPROVED PROCESS FOR THE PREPARATION OF IMIDAZOBENZODIAZEPINES | ODH IP Corp. (US) | 2024-03-21 | — | — | WO | disclosed |