Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 15/20 | 0.65 |
| ▸ | MMP2 | P08253 | 1/20 | 0.65 |
| ▸ | MMP3 | P08254 | 1/20 | 0.65 |
| ▸ | MMP7 | P09237 | 1/20 | 0.65 |
| ▸ | MMP9 | P14780 | 1/20 | 0.65 |
| ▸ | MMP8 | P22894 | 1/20 | 0.65 |
| ▸ | MMP13 | P45452 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076313 | 0.90 | MMP12 (0.68) | MMP12MMP2MMP3MMP7MMP9 | |
| SCHEMBL3081114 | 0.79 | MMP12 (1.00) | MMP12MMP2MMP3MMP7MMP9 | |
| SCHEMBL3083905 | 0.78 | KDM4E (0.48) | MMP12MMP2MMP3MMP9MMP13 | |
| SCHEMBL3084022 | 0.78 | MMP12 (0.78) | MMP12MMP2MMP3MMP7MMP9 | |
| SCHEMBL3084023 | 0.78 | MMP12 (0.78) | MMP12MMP2MMP3MMP7MMP9 | |
| SCHEMBL3088727 | 0.77 | MMP12 (0.79) | MMP12MMP2MMP3MMP7MMP9 | |
| SCHEMBL3088730 | 0.77 | MMP12 (0.79) | MMP12MMP2MMP3MMP7MMP9 | |
| SCHEMBL3124305 | 0.77 | MMP12 (0.75) | MMP12MMP2MMP3MMP7MMP9 | |
| SCHEMBL3079485 | 0.75 | MMP12 (0.93) | MMP12MMP2MMP3MMP7MMP9 | |
| SCHEMBL3078021 | 0.74 | MMP12 (0.91) | MMP12MMP2MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10669582-B2 | Massive parallel method for decoding DNA and RNA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-06-02 | — | — | US | disclosed |
| US-10669577-B2 | Massive parallel method for decoding DNA and RNA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-06-02 | — | — | US | disclosed |
| US-10662472-B2 | Massive parallel method for decoding DNA and RNA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-05-26 | — | — | US | disclosed |
| US-10648028-B2 | Massive parallel method for decoding DNA and RNA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-05-12 | — | — | US | disclosed |
| US-10633700-B2 | Massive parallel method for decoding DNA and RNA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-04-28 | — | — | US | disclosed |
| US-10577652-B2 | Massive parallel method for decoding DNA and RNA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-03-03 | — | — | US | disclosed |
| US-10570446-B2 | Massive parallel method for decoding DNA and RNA | THE TRUSTEE OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-02-25 | — | — | US | disclosed |
| US-10457984-B2 | Massive parallel method for decoding DNA and RNA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-10-29 | — | — | US | disclosed |
| US-10435742-B2 | Massive parallel method for decoding DNA and RNA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-10-08 | — | — | US | disclosed |
| US-10428380-B2 | Massive parallel method for decoding DNA and RNA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-10-01 | — | — | US | disclosed |
| US-20080131895-A1 | Determining sequence of preferential DNA sequences | NATIONAL SCIENCE FOUNDATION | 2008-06-05 | — | — | US | disclosed |
| US-7345159-B2 | Massive parallel method for decoding DNA and RNA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-03-18 | — | — | US | disclosed |
| EP-1790736-A2 | Massive parallel method for decoding DNA and RNA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-05-30 | — | — | EP | disclosed |
| EP-1337541-B1 | Massive parallel method for decoding DNA and RNA | UNIV COLUMBIA (US) | 2007-03-07 | — | — | EP | disclosed |
| US-20040185466-A1 | to detect single nucleotide polymorphisms, genetic mutation, gene expression, forensic identification, disease association, DNA/genomic sequencing and translation/transcription analysis; solid phase synthesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK. | 2004-09-23 | — | — | US | disclosed |
| EP-1337541-A4 | MASSIVE PARALLEL METHOD FOR DECODING DNA AND RNA | UNIV COLUMBIA (US) | 2004-07-14 | — | — | EP | disclosed |
| US-6664079-B2 | Sequencing nucleic acid; obtain nucleotide sequences, incubate in reaction mixture, apply to solid support, determine nucleotide sequences | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2003-12-16 | — | — | US | disclosed |
| EP-1337541-A2 | Massive parallel method for decoding DNA and RNA | The Trustees of Columbia University in the City of New York (US) | 2003-08-27 | — | — | EP | disclosed |
| US-20020102586-A1 | Sequencing nucleic acid; obtain nucleotide sequences, incubate in reaction mixture, apply to solid support, determine nucleotide sequences | NATIONAL SCIENCE FOUNDATION | 2002-08-01 | — | — | US | disclosed |
| WO-2002029003-A2 | MASSIVE PARALLEL METHOD FOR DECODING DNA AND RNA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10435742-B2 | Massive parallel method for decoding DNA and RNA | RNGTT, NSUN2, RNMT | MMP12 1999/4885MMP2 810/4885MMP3 978/4885 |
| US-10662472-B2 | Massive parallel method for decoding DNA and RNA | RNGTT, NSUN2, RNMT | MMP12 1999/4885MMP2 810/4885MMP3 978/4885 |
| US-10633700-B2 | Massive parallel method for decoding DNA and RNA | RNGTT, NSUN2, RNMT | MMP12 1999/4885MMP2 810/4885MMP3 978/4885 |
| US-10457984-B2 | Massive parallel method for decoding DNA and RNA | RNGTT, NSUN2, RNMT | MMP12 1999/4885MMP2 810/4885MMP3 978/4885 |
| US-10648028-B2 | Massive parallel method for decoding DNA and RNA | RNGTT, NSUN2, RNMT | MMP12 1999/4885MMP2 810/4885MMP3 978/4885 |
| US-10577652-B2 | Massive parallel method for decoding DNA and RNA | RNGTT, NSUN2, RNMT | MMP12 1999/4885MMP2 810/4885MMP3 978/4885 |
| US-10669577-B2 | Massive parallel method for decoding DNA and RNA | RNGTT, NSUN2, RNMT | MMP12 1999/4885MMP2 810/4885MMP3 978/4885 |
| US-10570446-B2 | Massive parallel method for decoding DNA and RNA | RNGTT, NSUN2, RNMT | MMP12 1999/4885MMP2 810/4885MMP3 978/4885 |
| US-10669582-B2 | Massive parallel method for decoding DNA and RNA | RNGTT, NSUN2, RNMT | MMP12 1999/4885MMP2 810/4885MMP3 978/4885 |
| US-10428380-B2 | Massive parallel method for decoding DNA and RNA | RNGTT, NSUN2, POLM | MMP12 1959/4885MMP2 868/4885MMP3 941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.