SCHEMBL30881175

SCHEMBL30881175

CC(C)[C@H](NC(=O)CNC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ NOD1 Q9Y239 3/20 0.45
▸ BACE1 P56817 6/20 0.41
▸ CTSD P07339 3/20 0.41
▸ FOLH1 Q04609 2/20 0.40
▸ C3AR1 Q16581 1/20 0.39
▸ FNTA P49354 2/20 0.38
▸ FNTB P49356 2/20 0.38
▸ PGGT1B P53609 1/20 0.38
▸ DPP4 P27487 1/20 0.38
▸ DPP8 Q6V1X1 1/20 0.38
▸ DPP9 Q86TI2 1/20 0.38
▸ FURIN P09958 3/20 0.37
▸ PRSS1 P07477 1/20 0.37
▸ BACE2 Q9Y5Z0 1/20 0.36
▸ PTGS1 P23219 1/20 0.36
▸ GSTK1 Q9Y2Q3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29376100 0.90 BACE1 (0.48) NOD1BACE1CTSDFOLH1DPP4
SCHEMBL31031459 0.90 NOD1 (0.42) NOD1BACE1CTSDFOLH1DPP4
SCHEMBL31666024 0.89 NOD1 (0.40) NOD1C3AR1FNTAFNTBPGGT1B
SCHEMBL30414136 0.89 NOD1 (0.52) NOD1FOLH1C3AR1FNTAFNTB
SCHEMBL30768075 0.87 BACE1 (0.48) NOD1BACE1CTSDFOLH1BACE2
SCHEMBL29765278 0.87 BACE1 (0.48) NOD1BACE1CTSDFOLH1BACE2
SCHEMBL29533710 0.86 BACE1 (0.46) NOD1BACE1CTSDFOLH1DPP4
SCHEMBL20800175 0.86 GNPAT (0.49) NOD1FOLH1C3AR1FNTAFNTB
SCHEMBL30477363 0.85 BACE1 (0.46) NOD1BACE1CTSDFOLH1BACE2
SCHEMBL30087281 0.85 NOD1 (0.44) NOD1FNTAFNTBPGGT1BFURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091097-A1 COMBINATION TREATMENT REGIMES FOR TREATING CANCER BARINTHUS BIOTHERAPEUTICS NORTH AMERICA INC (US) 2026-04-02 — — US disclosed
US-20250381281-A1 METHODS OF MANUFACTURING PEPTIDE-BASED VACCINES BARINTHUS BIOTHERAPEUTICS NORTH AMERICA INC (US) 2025-12-18 — — US disclosed
EP-4608437-A2 COMBINATION TREATMENT REGIMES FOR TREATING CANCER Barinthus Biotherapeutics North America, Inc. (US) 2025-09-03 — — EP disclosed
EP-4608455-A1 SELF-ASSEMBLING NANOPARTICLES Barinthus Biotherapeutics North America, Inc. (US) 2025-09-03 — — EP disclosed
US-20250242015-A1 SELF-ASSEMBLING NANOPARTICLES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2025-07-31 — — US disclosed
US-12370255-B2 Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response BARINTHUS BIOTHERAPEUTICS NORTH AMERICA, INC. (US) 2025-07-29 — — US disclosed
US-20250127887-A1 Self-Assembling Nanoparticles Based On Amphiphilic Peptides BARINTHUS BIOTHERAPEUTICS NORTH AMERICA, INC. (US) 2025-04-24 — — US disclosed
US-20240269269-A1 Self-Assembling Nanoparticles VACCITECH NORTH AMERICA, INC. (US) 2024-08-15 — — US disclosed
CN-118103059-A Self-assembled nanoparticles based on amphiphilic peptides 巴林萨斯生物疗法北美公司 2024-05-28 — — CN disclosed
WO-2024092028-A2 COMBINATION TREATMENT REGIMES FOR TREATING CANCER VACCITECH NORTH AMERICA, INC. (US) 2024-05-02 — — WO disclosed
WO-2024092030-A1 SELF-ASSEMBLING NANOPARTICLES VACCITECH NORTH AMERICA, INC. (US) 2024-05-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127887-A1 Self-Assembling Nanoparticles Based On Amphiphilic Peptides IAPP, BRCA1, ANXA11 NOD1 112/4885BACE1 61/4885CTSD 2403/4885
US-20240269269-A1 Self-Assembling Nanoparticles UBE2B, CD4, UBE2G2 NOD1 114/4885BACE1 1895/4885CTSD 2805/4885
US-20260091097-A1 COMBINATION TREATMENT REGIMES FOR TREATING CANCER IL2, IFNG, ICOS NOD1 1790/4885BACE1 1452/4885CTSD 127/4885
US-20250242015-A1 SELF-ASSEMBLING NANOPARTICLES UBE2B, CD4, HRH1 NOD1 112/4885BACE1 1908/4885CTSD 2836/4885
US-20250381281-A1 METHODS OF MANUFACTURING PEPTIDE-BASED VACCINES VIP, HM13, SPPL2B NOD1 553/4885BACE1 1040/4885CTSD 2138/4885
US-12370255-B2 Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response MYD88, ICOS, CD4 NOD1 405/4885BACE1 1959/4885CTSD 1430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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