Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | ACVR2B | Q13705 | 1/20 | 0.37 |
| ▸ | MYLK | Q15746 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.37 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30881916 | 0.91 | DGAT1 (0.41) | DGAT1GRM2CCNT1CDK9KMT2A | |
| SCHEMBL30881836 | 0.84 | KEAP1 (0.44) | GRM2CCNT1CDK9KMT2AATM | |
| SCHEMBL30881704 | 0.80 | RPS6KB1 (0.42) | DGAT1GRM2CCNT1CDK9PRKD3 | |
| SCHEMBL30881732 | 0.79 | SLC22A12 (0.41) | GRM2 | |
| SCHEMBL30881867 | 0.79 | KDM4E (0.38) | DGAT1GRM2KMT2APRKD3MAPK9 | |
| SCHEMBL2523960 | 0.77 | DGAT1 (0.50) | DGAT1KMT2APARP1ERN1 | |
| SCHEMBL21828961 | 0.77 | KMT2A (0.60) | DGAT1KMT2AATMRXFP1ERN1 | |
| SCHEMBL30881904 | 0.75 | ALDH1A1 (0.48) | CCNT1CDK9KMT2APRKD3MAPK9 | |
| SCHEMBL1927478 | 0.74 | BCAT2 (0.61) | GRM2PARP1BCAT2MAP2 | |
| SCHEMBL30881799 | 0.74 | RPS6KB1 (0.39) | CCNT1CDK9KMT2APARP1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026880-A | Aryl amide compound, pharmaceutical composition containing same and application thereof | 华东师范大学 | 2024-05-14 | — | — | CN | disclosed |