Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 13/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885428 | 0.85 | STING1 (0.55) | STING1MAPTKDM4EALDH1A1 | |
| SCHEMBL30885433 | 0.84 | STING1 (0.53) | STING1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL30885423 | 0.82 | STING1 (0.51) | STING1MAPT | |
| SCHEMBL30885386 | 0.82 | STING1 (0.58) | STING1MAPTTRPV1KDM4EALDH1A1 | |
| SCHEMBL30885377 | 0.81 | STING1 (0.49) | STING1MAPT | |
| SCHEMBL30386673 | 0.80 | STING1 (0.72) | STING1MAPTRAB9ATRPV1 | |
| SCHEMBL28991332 | 0.80 | STING1 (0.72) | STING1MAPTRAB9ATRPV1 | |
| SCHEMBL30885399 | 0.79 | STING1 (0.52) | STING1MAPTKDM4EALDH1A1 | |
| SCHEMBL30885374 | 0.78 | STING1 (0.48) | STING1MAPTSMN1; SMN2TRPV1 | |
| SCHEMBL30885458 | 0.78 | STING1 (0.53) | STING1MAPTNPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756698-A | Urea compound and medical application thereof as STING inhibitor | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |