Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 6/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 3/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25325827 | 0.90 | BRD4 (0.44) | MAT2AKDM4EBRD4CREBBP | |
| SCHEMBL25320390 | 0.80 | TLR8 (0.39) | TLR8 | |
| SCHEMBL30886292 | 0.74 | CREBBP (0.44) | BRD4CREBBP | |
| SCHEMBL24364283 | 0.73 | PRKCZ (0.42) | BRD4CREBBP | |
| SCHEMBL30886382 | 0.73 | TDO2 (0.36) | TLR8 | |
| SCHEMBL30886424 | 0.73 | KDM4E (0.37) | KDM4E | |
| SCHEMBL30886362 | 0.72 | ERCC1 (0.43) | CREBBP | |
| SCHEMBL24365178 | 0.71 | CLK1 (0.49) | — | |
| SCHEMBL31430205 | 0.71 | MAT2A (0.35) | MAT2A | |
| SCHEMBL25326041 | 0.70 | GRM5 (0.38) | GRM5GRM1KDM4EKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118047793-A | Pyridine derivative and application thereof | 成都百裕制药股份有限公司 | 2024-05-17 | — | — | CN | disclosed |