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Sugi Predict / Compounds / SCHEMBL30891448

SCHEMBL30891448

SCHEMBL30891448

C[C@@H]1O[C@@H](OCCNC(=O)CCCCCNC(=O)CN(CC(=O)NCCCCCNC(=O)CN(CC(=O)NCCCCCC(=O)O)CC(=O)NCCCC[C@@H](C(=O)NCCO[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)N(CC(=O)NCCO[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)CC(=O)NCCO[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)CC(=O)NCCO[C@H]2O[C@H](CO[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H](O)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H]2O)[C@@H](O)[C@H](O)[C@@H]1O

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MMP13 P45452 1/20 0.42
▸ FGF1 P05230 1/20 0.40
▸ FGF2 P09038 1/20 0.40
▸ VEGFA P15692 1/20 0.40
▸ HPSE Q9Y251 1/20 0.40
▸ SELP P16109 6/20 0.40
▸ CD209 Q9NNX6 2/20 0.39
▸ SELL P14151 5/20 0.37
▸ MDK P21741 1/20 0.37
▸ SELE P16581 7/20 0.36
▸ ALDH1A1 P00352 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ ALOX15 P16050 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ IGF2R P11717 2/20 0.34
▸ GJB2 P29033 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30891411 1.00 MMP13 (0.42) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL32664918 0.99 MMP13 (0.40) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL30891289 0.96 MMP13 (0.43) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL32664801 0.95 SELP (0.43) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL32664921 0.92 SELP (0.45) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL32664862 0.91 MMP13 (0.44) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL32664864 0.90 SELP (0.40) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL30891415 0.90 MMP13 (0.42) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL30891315 0.90 MMP13 (0.41) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL30891466 0.90 MMP13 (0.41) MMP13FGF1FGF2VEGFAHPSE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260021190-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES MERCK SHARP & DOHME LLC (US) 2026-01-22 — — US disclosed
EP-4615487-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES Merck Sharp & Dohme LLC (US) 2025-09-17 — — EP disclosed
WO-2024102633-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES MERCK SHARP & DOHME LLC (US) 2024-05-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021190-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES INSR, GPR119, GLP1R MMP13 1271/4885FGF1 1543/4885FGF2 2234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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