Sugi Predict

Sugi Predict / Compounds / SCHEMBL30891315

SCHEMBL30891315

SCHEMBL30891315

C[C@@H]1O[C@@H](OCCNC(=O)CCCCCNC(=O)CN(CC(=O)NCCCCCNC(=O)CN(CC(=O)NCCCCCC(=O)OCc2ccccc2)CC(=O)NCCCC[C@@H](C(=O)NCCO[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)N(CC(=O)NCCO[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)CC(=O)NCCO[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)CC(=O)NCCO[C@H]2O[C@H](CO[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H](O)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H]2O)[C@@H](O)[C@H](O)[C@@H]1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MMP13 P45452 2/20 0.41
▸ FGF1 P05230 1/20 0.37
▸ FGF2 P09038 1/20 0.37
▸ VEGFA P15692 1/20 0.37
▸ HPSE Q9Y251 1/20 0.37
▸ EPOR P19235 6/20 0.36
▸ SIRT2 Q8IXJ6 1/20 0.36
▸ LGALS8 O00214 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ CYP3A4 P08684 1/20 0.36
▸ ALOX15 P16050 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ SELE P16581 1/20 0.35
▸ SELP P16109 2/20 0.35
▸ MDK P21741 1/20 0.35
▸ CD209 Q9NNX6 1/20 0.34
▸ MMP2 P08253 1/20 0.34
▸ MMP3 P08254 1/20 0.34
▸ MMP9 P14780 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30891466 1.00 MMP13 (0.41) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL32664935 0.99 MMP13 (0.40) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL30891384 0.99 MMP13 (0.40) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL30891367 0.97 MMP13 (0.42) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL30891493 0.91 MMP13 (0.41) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL30891399 0.90 MMP13 (0.41) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL30891448 0.90 MMP13 (0.42) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL30891411 0.90 MMP13 (0.42) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL32664920 0.90 MMP13 (0.41) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL15130853 0.89 MMP13 (0.47) MMP13FGF1FGF2VEGFAHPSE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260021190-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES MERCK SHARP & DOHME LLC (US) 2026-01-22 — — US disclosed
EP-4615487-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES Merck Sharp & Dohme LLC (US) 2025-09-17 — — EP disclosed
WO-2024102633-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES MERCK SHARP & DOHME LLC (US) 2024-05-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021190-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES INSR, GPR119, GLP1R MMP13 1271/4885FGF1 1543/4885FGF2 2234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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