⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5671464 | 0.92 | OPRM1 (0.32) | — | |
| SCHEMBL10821059 | 0.84 | OPRM1 (0.39) | — | |
| SCHEMBL309264 | 0.84 | ADRB2 (0.42) | — | |
| SCHEMBL10002595 | 0.82 | — | — | |
| SCHEMBL22444769 | 0.82 | OPRM1 (0.48) | — | |
| SCHEMBL28651942 | 0.80 | OPRM1 (0.46) | — | |
| SCHEMBL29137154 | 0.80 | OPRM1 (0.46) | — | |
| SCHEMBL28647834 | 0.80 | OPRM1 (0.46) | — | |
| SCHEMBL22444770 | 0.80 | OPRM1 (0.46) | — | |
| SCHEMBL7617286 | 0.80 | DNM1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143408-B2 | N-(8-heteroaryltetrahydronaphtalene-2yl) or N-(5-heteroarylchromane-3-yl) carboxamide derivatives for the treatment of pain | ASTRAZENECA AB (SE) | 2012-03-27 | — | — | US | claimed |
| US-20100137322-A1 | NOVEL N-(8-HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N-(5-HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2010-06-03 | — | — | US | claimed |
| EP-2158198-A2 | NOVEL N- (8HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N- (5- HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | AstraZeneca AB (SE) | 2010-03-03 | — | — | EP | claimed |
| WO-2008130320-A2 | NOVEL N- (8-HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N- (5- HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | claimed |
| EP-4390548-A1 | COMPOUND FOR FORMING METAL-CONTAINING FILM, COMPOSITION FOR FORMING METAL-CONTAINING FILM, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2024-06-26 | — | — | EP | disclosed |
| CN-113574041-B | Bisphenol production method and polycarbonate resin production method | 三菱化学株式会社 | 2023-10-13 | — | — | CN | disclosed |
| CN-113574041-A | Method for producing bisphenol and method for producing polycarbonate resin | 三菱化学株式会社 | 2021-10-29 | — | — | CN | disclosed |
| CN-113142222-A | Bactericide composition | 侨昌现代农业有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-113142235-A | Bactericide composition | 侨昌现代农业有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-113142231-A | Bactericide composition | 侨昌现代农业有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-113142229-A | Bactericide composition | 侨昌现代农业有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-113142219-A | Bactericide composition | 侨昌现代农业有限公司 | 2021-07-23 | — | — | CN | disclosed |
| EP-1090967-A2 | Composition for film formation, method of film formation, and insulating film | JSR Corporation (JP) | 2001-04-11 | — | — | EP | disclosed |
| EP-1088868-A2 | Composition for film formation, method of film formation, and insulating film | JSR Corporation (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0194885-B1 | AZO COMPOUND AND AQUEOUS INK COMPOSITION COMPRISING THE SAME | TAOKA CHEMICAL CO., LTD (JP) | 1989-06-07 | — | — | EP | disclosed |
| US-4771129-A | MAGENTA COLOR FOR AQUEOUS INK COMPOSITION | TAOKA CHEMICAL COMPANY, LIMITED (JP) | 1988-09-13 | — | — | US | disclosed |
| EP-0168961-B1 | AN AQUEOUS INK COMPOSITION | TAOKA CHEMICAL CO., LTD (JP) | 1988-03-23 | — | — | EP | disclosed |
| EP-0194885-A1 | Azo compound and aqueous ink composition comprising the same | TAOKA CHEMICAL CO., LTD (JP) | 1986-09-17 | — | — | EP | disclosed |
| US-4605442-A | STORAGE STABILITY, JET STABILITY, IMAGE CLARITY | TAOKA CHEMICAL COMPANY, LIMITED (JP) | 1986-08-12 | — | — | US | disclosed |
| EP-0168961-A2 | An aqueous ink composition | TAOKA CHEMICAL CO., LTD (JP) | 1986-01-22 | — | — | EP | disclosed |