Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23540991 | 1.00 | NPSR1 (0.38) | NPSR1ALDH1A1HTTTDP1GPR35 | |
| SCHEMBL31720604 | 0.85 | TDP1 (0.46) | NPSR1ALDH1A1HTTTDP1GPR35 | |
| SCHEMBL30936620 | 0.84 | ALDH1A1 (0.44) | NPSR1ALDH1A1HTTTDP1L3MBTL1 | |
| SCHEMBL30936632 | 0.84 | NPSR1 (0.38) | NPSR1ALDH1A1HTTTDP1GPR35 | |
| SCHEMBL7476967 | 0.83 | TSHR (0.50) | NPSR1ALDH1A1HTTTDP1TSHR | |
| SCHEMBL25171636 | 0.82 | LMNA (0.33) | NPSR1ALDH1A1HTTTDP1LMNA | |
| SCHEMBL31220170 | 0.82 | LMNA (0.33) | NPSR1ALDH1A1HTTTDP1LMNA | |
| SCHEMBL7480695 | 0.81 | ALDH1A1 (0.45) | NPSR1ALDH1A1TSHRL3MBTL1LMNA | |
| SCHEMBL30893241 | 0.80 | MAPT (0.36) | NPSR1ALDH1A1HTTTDP1LMNA | |
| SCHEMBL4613668 | 0.79 | ALDH1A1 (0.38) | NPSR1ALDH1A1HTTMAPTNR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097948-A1 | DEGRADERS OF MDM2 AND USES THEREOF | ROIVANT DISCOVERY, INC. (US) | 2024-05-10 | — | — | WO | disclosed |